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Skin pathology


Skin cancer is a major health issue in Australia. In 2013, melanoma was the fourth most commonly diagnosed cancer in Australia and is expected to remain the same to date with more than 14,000 new melanoma cases. Basal and squamous cell carcinomas of the skin are the most frequently diagnosed cancers in Australia even though they are not included in cancer statistics. A recent study showed that more than 23% of all questions posed to GPs in the survey group, by their patients, related to skin pathology.


Dr Blake O'Brien discusses  identification of BAP-oma, determining whether it is likely to be sporadic or part of an inherited tumour syndrome; and the importance of BAP-oma in identifying risks for other tumours.

Granulomatous reaction pattern

Dr Blake O'Brien discusses the five types of granulomas - sarcoidal, tuberculoid, necrobiotic, supprative and foreign-body - and what they look like, as well as the main causes of each.

Intraepidermal vesiculobullous diseases

Prof David Weedon gives this presentation on intraepidermal vesiculobullous diseases,  and discusses determining the anatomical level of the split, and the mechanisms responsible to assist in diagnosis.

The lichenoid reaction pattern

Prof David Weedon  - author of Weedon's Skin Pathology - presents this discussion on the lichenoid reaction pattern, filmed in front of Australian dermatology registrars.

Approach to skin biopsies

Prof David Weedon  gives a brief history of dermatopathology and introduces the approach to skin biopsies. 

The spongiotic tissue reaction

Prof David Weedon presents a discussion on the spongiotic tissue reaction and all of its subtypes.

The psoriasiform reaction pattern

Dr Blake O'Brien gives this presentation on the psoriasiform reaction pattern, discussing the causes of, and differentials for classic psoriasis, as well as many psoriasis subtypes, and lichen simplex chronicus among others.