On average, there are about 20 skin cancers per year per general practitioner in Australia. There is significant morbidity and mortality associated with skin cancer. Each year, about 1,500 Australians die from melanoma and 450 from non-melanoma skin cancers (NMSCs). As with most cancers, the risk of developing skin cancer increases with age. Fortunately, skin cancer is amenable to early detection and potential cure. GPs are well placed to facilitate the detection of skin cancer by using opportunistic examination, a high index of suspicion and good observation skills. These videos will discuss the microscopy of a range of different lesions and their particular cytological characteristics.
Basal cell carcinoma - aggressive types
Dr Jason Gluch discusses the more aggressive forms of basal cell carcinoma (BCC), including scelorising BCC (AKA morphoeic, fibrosing or serous), infiltrating BCC and micro-nodular BCC.
AFX - A diagnosis of exclusion
Dr Louis Pool talks through the histology of atypical fibroxanthomas (AFX) and explains why AFX is a diagnosis of exclusion and why immunohistochemistry is required to get to a definite histological diagnosis.
The mysterious lentigo
Do you know the true meaning of lentigo? It is one of the most nebulous terms in dermatopathology, used for a variety of lesions including melanocyctic and non-melanocytic, malignant and benign. Dr Jill Magee clarifies the confusion surrounding the mysterious lentigo and presents a number of cases for consideration including solar lentigo, lentigo simplex, lentigo maligna and dysplastic lentiginous naevus.
From solar keratosis to SCC - exploring squamous dysplasia
Dr Lisa Wilkinson explores the architectural abnormalities in epidermis showing dysplasia and clarifies the subtle differences between three types of squamous dysplasia including solar keratosis, intraepidermal carcinoma and sqaumous cell carcinoma.
The lichenoid reaction pattern
Dr Blake O'Brien presents a guided microscopy session exploring the histological features of the lichenoid reaction pattern including the changes that occur associated with keratinocyte apoptosis. The demonstration includes examples of neoplastic and inflammatory conditions including benign lichenoid keratosis and lupus.
Is it really an SCC? How to spot a Keratoacanthoma
Dr Angus Collins guides the viewer through how to identify a keratoacanthoma under the microscope and how to distinguish this lesion from a well differentiated squamous cell carcinoma (SCC). Examples include both active and regressed keratoacanthomas as well as SCCs.
Dr Angus Collins describes the microscopic features of normal skin, including its layers and structures.
Synonymous terms used by clinicians include dermatitis and eczematous dermatitis to describe spongiotic dermatitis. However, Dr Blake O'Brien, dermatopathologist at SNP, will talk about the histologic features that define dermatitis as spongiotic and discus some of the common causes.
Squamous cell carcinoma
Squamous cell carcinomas (SCCs) are the second most frequently diagnosed carcinoma, behind BCCs. Dr Fiona Lehane reviews cases to provide details of various SCC features and explores the use of ancillary stains used to assist in the diagnosis of differentiated, moderately differentiated and poorly differentiated tumours.
Two cases of leukocytoclastic vasculitis, also known as hypersensitivity vasculitis are presented by Dr Jill Magee. Inflammatory changes are described and the myriad of causes are considered.
Basal cell carcinoma - Non-aggressive types
Dr Jason Gluch, dermatopathologist, gives an introduction into the most common skin tumour, Basal Cell Carcinoma (BCC), in particular the non-aggressive types.
Dr Jill Magee, dermatopathologist, presents a guided microscopy case on Erythema nodosum, a type of panniculitis that presents with red bumps, usually on the lower extremities of young patients (10-30 years old).